Mandelate Racemase/muconate Lactonizing Enzyme/enolase Superfamily

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-135   PRO-136  7.5 7.1 7.6 3.2 75.2 71.8 44.1
 PRO-136   TYR-137  4.8 4.7 4.8 -14.6 99.3 94.0 30.6
 TYR-137   ALA-138  1.0 1.1 3.5 -19.3 99.3 93.2 51.8
 ALA-138   SER-139  3.2 3.5 12.4 12.7 43.2 47.8 64.3
 SER-139   LEU-140  5.6 5.7 -7.7 20.0 74.4 65.1 -40.6
 LEU-140   LEU-141  8.8 8.5 -4.3 -0.5 128.5 125.9 -40.3
 LEU-141   PHE-142  12.1 12.0 -11.1 -4.5 62.1 69.1 42.6
 PHE-142   GLY-143  13.9 13.9 1.9 -4.6 118.5 117.6 -22.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-250   ALA-251  7.6 7.7 -1.2 8.7 94.5 95.7 1.4
 ALA-251   GLY-252  3.9 4.0 -2.5 6.9 64.1 60.0 7.4
 GLY-252   GLY-253  2.8 2.2 -15.5 8.8 71.4 81.5 33.2
 GLY-253   GLU-254  3.4 2.9 1.1 2.0 67.1 64.5 37.7
 GLU-254   ALA-255  6.4 5.7 1.4 -19.8 126.6 116.7 51.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-260   MET-261  6.5 6.8 -13.4 -0.9 69.0 65.9 -1.7
 MET-261   ALA-262  5.1 5.0 1.1 5.7 131.5 129.6 -18.3
 ALA-262   GLN-263  4.1 4.2 0.7 -2.3 61.0 56.9 2.4
 GLN-263   HIS-264  4.6 4.8 5.4 8.2 64.7 64.9 31.3
 HIS-264   LEU-265  1.3 1.3 -5.9 -6.5 49.1 49.5 17.6
 LEU-265   MET-266  1.0 1.5 3.3 -0.7 104.5 97.6 14.0
 MET-266   ASP-267  4.1 4.8 -3.2 -16.2 138.7 139.2 -57.4
 ASP-267   TYR-268  5.4 6.0 -3.4 16.3 108.5 114.5 24.0
 TYR-268   GLY-269  5.1 4.9 -10.0 -1.8 43.4 46.6 82.9
 GLY-269   ARG-270  5.5 5.5 2.2 -9.5 127.2 123.5 28.5
 ARG-270   ILE-271  7.9 7.8 1.1 6.3 166.7 171.8 -42.0
 ILE-271   GLY-272  5.9 6.2 5.1 -9.8 116.8 118.7 -25.4
 GLY-272   PHE-273  7.3 7.9 0.2 7.9 119.1 131.6 -22.8
 PHE-273   ILE-274  4.3 5.1 -8.9 5.6 122.9 119.2 -0.7
 ILE-274   GLN-275  2.8 3.5 2.6 5.7 134.8 136.0 -32.6
 GLN-275   ILE-276  3.2 3.0 -3.0 1.4 114.2 112.2 -8.9
 ILE-276   ASP-277  6.8 6.6 -3.3 1.6 52.1 53.0 -0.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees