Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
7.0
6.7
-1.5
-9.6
45.5
50.9
42.6
LYS-114
GLY-115
6.4
5.7
-14.4
-15.2
76.6
74.7
32.6
GLY-115
PRO-116
2.6
2.0
17.5
10.3
93.5
114.8
-28.0
PRO-116
GLU-117
2.9
3.5
-99.3
90.6
23.3
35.2
17.1
GLU-117
ILE-118
5.4
5.2
5.6
-32.9
88.2
93.3
26.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-215
ASP-216
10.2
9.9
-19.6
31.9
21.3
15.5
-80.7
ASP-216
LEU-217
10.8
11.1
-12.4
-10.8
50.1
49.2
59.5
LEU-217
PRO-218
8.0
8.1
-11.2
-22.4
50.9
69.5
71.5
PRO-218
ALA-219
6.2
6.1
-6.2
-8.4
114.4
104.6
-22.2
ALA-219
VAL-220
4.6
3.5
25.7
-14.9
91.6
129.3
-38.2
VAL-220
SER-221
1.0
1.5
-54.3
15.5
77.8
59.0
44.1
SER-221
GLU-222
3.3
3.6
2.8
6.1
151.9
151.2
-10.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees