Major Prion Protein

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-188   VAL-189  9.7 9.5 1.6 11.5 29.2 26.5 6.3  VAL-189   THR-190  9.4 9.5 -30.7 6.5 111.0 108.7 -6.7  THR-190   THR-191  7.3 7.2 -176.1 18.3 83.6 63.2 25.3  THR-191   THR-192  3.6 4.8 156.2 110.3 111.4 71.4 3.7  THR-192   THR-193  1.7 6.0 164.6 9.3 104.7 24.4 -52.0  THR-193   LYS-194  3.1 5.0 -172.3 -17.7 6.3 93.2 91.1  LYS-194   GLY-195  3.9 1.3 18.2 150.5 120.1 114.1 -30.0  GLY-195   GLU-196  6.4 4.0 58.1 -37.7 111.9 173.0 -12.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees