Bifunctional P-450/nadph-P450 Reductase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-166   ARG-167  7.8 7.6 -1.0 -2.4 67.3 66.9 -3.4
 ARG-167   ASP-168  4.2 4.0 -1.8 -16.6 38.2 42.7 134.8
 ASP-168   GLN-169  2.7 1.9 29.7 -14.0 82.2 78.5 7.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-215   VAL-216  3.5 3.6 -4.4 -1.6 29.0 30.6 13.4
 VAL-216   ASP-217  2.9 2.7 -2.1 6.7 51.6 50.4 2.2
 ASP-217   LYS-218  4.7 4.8 -4.3 -4.1 103.7 98.9 13.6
 LYS-218   ILE-219  4.6 5.1 -5.6 13.3 70.8 74.4 -13.7
 ILE-219   ILE-220  2.5 2.9 -9.9 3.9 12.8 13.0 22.9
 ILE-220   ALA-221  2.4 2.7 4.0 -24.4 100.5 105.4 51.5
 ALA-221   ASP-222  6.2 6.2 10.9 -3.7 80.4 74.0 -1.9
 ASP-222   ARG-223  7.4 8.1 3.5 13.5 133.2 122.9 -51.8
 ARG-223   LYS-224  7.1 7.7 -8.1 2.0 35.3 29.3 39.4
 LYS-224   ALA-225  7.5 8.0 6.1 -20.5 82.1 87.0 0.3
 ALA-225   SER-226  10.9 11.4 31.0 -29.5 86.5 75.2 -53.5
 SER-230   ASP-231  13.5 13.8 -2.7 12.8 52.1 65.7 1.9
 ASP-231   ASP-232  14.0 14.7 -52.6 52.3 126.7 132.6 -6.0
 ASP-232   LEU-233  12.5 12.9 -8.6 2.1 71.1 68.4 18.4
 LEU-233   LEU-234  10.9 11.2 -2.4 5.9 61.1 59.4 -6.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees