Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-641   PHE-642  7.0 6.2 -33.2 -1.7 86.6 90.9 2.9
 PHE-642   GLY-643  3.7 2.9 -24.2 -25.3 93.0 58.5 13.8
 GLY-643   LEU-644  5.7 2.9 14.9 30.7 58.6 60.1 51.4
 LEU-644   ALA-645  4.1 5.0 -23.6 -13.9 69.9 107.2 0.4
 ALA-645   ARG-646  1.9 4.7 153.1 76.4 116.2 135.1 -143.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-664   LYS-665  2.8 2.8 19.6 -0.7 113.6 118.9 -0.2
 LYS-665   TRP-666  2.3 2.5 7.5 1.1 54.1 53.0 0.5
 TRP-666   MET-667  2.6 3.1 1.1 8.7 73.2 74.4 4.4
 MET-667   ALA-668  2.4 2.2 0.9 2.9 125.7 117.1 1.4
 ALA-668   PRO-669  6.1 6.0 1.8 -16.9 115.4 124.5 11.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees