Hiv-1 Rt A-Chain

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-216   PRO-217  21.8 22.5 -57.6 11.4 27.0 27.8 93.0  PRO-217   ASP-218  19.4 21.5 24.4 15.5 90.2 94.9 2.9  ASP-218   LYS-219  19.4 19.8 -144.0 -51.4 87.6 92.3 -124.3  LYS-219   LYS-220  16.9 16.6 114.5 -44.1 144.3 19.0 -5.9  LYS-220   HIS-221  15.9 15.7 152.7 58.0 104.4 97.7 -147.7  HIS-221   GLN-222  14.9 12.1 47.7 23.9 35.3 74.8 165.8  GLN-222   LYS-223  14.0 13.6 -81.3 117.8 90.7 101.8 70.4  LYS-223   GLU-224  10.7 11.6 -40.0 -1.8 139.4 41.4 56.5  GLU-224   PRO-225  8.0 8.9 -75.4 40.6 86.1 116.9 9.5  PRO-225   PRO-226  4.3 5.9 138.3 -1.7 147.2 92.4 -35.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-228   TRP-229  7.6 8.1 10.2 -15.4 119.2 132.3 17.3  TRP-229   MET-230  10.0 9.9 -23.6 43.3 71.7 67.6 -5.7  MET-230   GLY-231  13.3 12.3 -27.3 -23.0 84.8 108.9 -10.6  GLY-231   TYR-232  13.0 11.6 57.5 -23.9 99.0 111.1 14.9  TYR-232   GLU-233  9.6 8.1 2.4 -19.1 58.9 59.6 -6.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-311   GLU-312  18.6 18.9 18.3 22.4 106.7 117.6 -37.9  GLU-312   PRO-313  16.7 17.4 -5.2 -5.1 56.2 84.3 0.7  PRO-313   VAL-314  13.2 13.6 -7.9 7.9 25.1 21.2 0.5  VAL-314   HIS-315  12.8 11.8 -23.1 -29.6 74.0 89.8 9.0  HIS-315   GLY-316  9.7 8.7 22.0 -80.2 170.5 154.3 127.7  GLY-316   VAL-317  8.4 7.1 45.1 -12.0 98.0 95.2 -20.8  VAL-317   TYR-318  5.7 4.7 -7.4 -1.4 55.9 51.6 3.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees