Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-714   GLY-715  8.3 7.9 -10.9 -5.8 73.8 75.7 44.2  GLY-715   PRO-716  4.6 4.1 12.8 -13.8 94.8 106.0 25.7  PRO-716   GLU-717  2.4 2.3 -90.0 81.1 35.9 30.0 58.4  GLU-717   ILE-718  5.1 5.1 -1.0 6.0 85.4 85.9 6.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  VAL-815   ASP-816  7.6 7.0 -9.6 -8.6 15.2 19.0 24.5  ASP-816   LEU-817  8.4 7.9 2.5 4.4 124.0 133.7 16.0  LEU-817   PRO-818  5.3 5.2 3.9 -10.3 125.9 121.5 18.4  PRO-818   ALA-819  3.7 3.2 -6.1 -7.8 112.9 112.4 -10.7  ALA-819   VAL-820  3.6 2.6 11.8 -8.9 98.1 120.5 -8.6  VAL-820   SER-821  1.9 1.9 -30.4 -8.0 77.3 63.7 92.1  SER-821   GLU-822  3.1 2.7 -1.4 3.7 23.0 33.2 -12.0  GLU-822   LYS-823  5.1 4.9 3.6 -2.5 85.5 77.4 -13.4  LYS-823   ASP-824  7.7 7.6 -2.9 -6.9 90.3 96.5 8.1  ASP-824   ILE-825  6.3 6.2 17.1 -13.0 153.7 153.5 -6.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees