Huzaf Antibody Heavy Chain

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-123   SER-124  2.9 2.9 7.1 -22.4 73.3 69.8 23.6
 SER-124   VAL-125  5.5 5.6 -15.8 21.0 157.2 164.8 83.4
 VAL-125   PHE-126  4.5 4.6 22.5 -21.7 49.2 53.1 -84.3
 PHE-126   PRO-127  6.9 6.9 -6.3 3.3 158.9 157.8 -93.0
 PRO-127   LEU-128  6.7 6.6 5.6 -11.6 57.3 54.9 100.6
 LEU-128   ALA-129  6.4 6.2 -28.4 23.4 145.0 152.3 -152.4
 ALA-129   PRO-130  7.7 7.5 1.8 -3.7 21.8 29.8 14.8
 PRO-130   SER-131  6.7 7.1 -1.2 -65.3 117.4 111.8 -527.1
 SER-131   SER-132  9.5 10.3 -53.0 -141.3 134.1 164.5 2519.0
 SER-132   LYS-133  11.9 10.6 -177.5 37.5 158.6 124.7 -1974.4
 LYS-133   SER-134  11.1 11.1 -70.9 66.5 85.2 158.3 -40.8
 SER-134   THR-135  10.5 9.6 -63.2 -140.0 118.2 124.1 1200.7
 THR-135   SER-136  8.3 7.3 154.7 37.2 23.6 82.5 -1979.9
 SER-136   GLY-137  8.0 6.7 -70.1 102.9 113.4 45.5 -73.0
 GLY-137   GLY-138  4.4 5.0 -79.3 2.3 59.4 84.8 401.9
 GLY-138   THR-139  1.6 1.5 -71.7 34.3 32.5 16.8 421.3
 THR-139   ALA-140  1.1 1.0 12.8 -14.5 130.9 126.8 53.4
 ALA-140   ALA-141  2.6 2.8 -27.9 17.1 34.4 30.1 72.4
 ALA-141   LEU-142  2.9 3.1 -19.9 3.4 47.1 41.3 63.7
 LEU-142   GLY-143  2.7 2.8 -9.3 -4.1 36.6 39.7 251.5
 GLY-143   CYS-144  1.9 1.6 17.4 -2.3 150.1 150.5 -305.4
 CYS-144   LEU-145  2.4 2.3 13.9 -16.3 119.7 118.7 -24.6
 LEU-145   VAL-146  4.9 4.8 -36.3 37.4 22.4 11.5 -4.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-182   SER-183  7.5 7.7 18.3 -11.6 137.3 131.4 -151.7
 SER-183   SER-184  6.0 6.0 -0.1 3.3 64.3 56.6 -17.8
 SER-184   VAL-185  4.3 4.2 0.2 -3.6 144.1 148.2 59.3
 VAL-185   VAL-186  3.4 3.4 -9.8 3.0 54.6 54.5 -23.2
 VAL-186   THR-187  3.2 3.3 -11.8 12.8 28.8 30.2 -144.0
 THR-187   VAL-188  2.8 2.8 -14.3 5.2 65.9 64.7 213.6
 VAL-188   PRO-189  3.0 2.8 -5.0 4.0 28.9 38.1 3.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-206   SER-207  6.2 5.9 -15.7 5.4 65.0 67.1 122.0
 SER-207   ASN-208  2.8 2.8 5.6 1.2 79.3 80.7 -6.5
 ASN-208   THR-209  5.9 6.1 -4.3 13.3 128.8 134.2 102.7
 THR-209   LYS-210  4.5 5.0 32.4 -36.1 25.4 35.4 -15.0
 LYS-210   VAL-211  6.5 7.0 -12.4 -8.4 119.4 119.3 1.9
 VAL-211   ASP-212  6.4 6.8 -0.3 -6.0 159.7 168.4 -116.6
 ASP-212   LYS-213  8.0 8.0 2.8 -4.6 67.1 70.2 -11.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees