Nad-Dependent Deacetylase Sirtuin-6

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-131   GLY-132  4.6 4.6 -4.2 9.3 146.3 148.2 60.6
 GLY-132   ASN-133  1.6 1.7 2.9 -8.7 65.2 65.8 -47.1
 ASN-133   MET-134  2.3 2.3 -7.3 0.5 164.8 164.0 -26.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-189   LEU-190  10.4 10.4 -19.6 2.0 85.4 80.9 -164.9
 LEU-190   PRO-191  6.7 6.7 4.0 -9.2 87.0 87.9 -92.7
 PRO-191   ASP-192  5.5 5.6 1.0 1.7 16.4 16.1 93.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees