Acid-Sensing Ion Channel

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-60   VAL-61  13.4 12.5 43.9 -25.6 68.7 85.5 -7.2
 VAL-61   CYS-62  9.9 9.3 -10.7 12.8 174.0 164.6 24.3
 CYS-62   THR-63  10.8 10.7 9.9 -1.6 61.0 66.7 36.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-433   ILE-434  4.2 5.3 3.8 22.1 61.3 59.4 52.1
 ILE-434   GLY-435  7.6 7.9 -12.2 -8.7 69.4 84.1 33.2
 GLY-435   GLY-436  10.0 10.6 5.1 9.8 43.7 33.9 54.3
 GLY-436   GLN-437  11.5 11.4 -21.8 6.3 119.7 123.0 -27.9
 GLN-437   MET-438  11.5 11.8 26.8 -9.3 119.4 113.4 3.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees