Coagulation Factor VIII Light Chain

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-2168   CYS-2169  10.0 10.1 0.0 0.0 87.4 87.4 0.0  CYS-2169   ASP-2170  7.0 7.0 0.0 0.0 68.9 68.9 0.0  ASP-2170   LEU-2171  3.5 3.5 1.1 -30.0 164.9 164.8 29.6  LEU-2171   ASN-2172  2.2 1.8 14.2 -102.7 138.2 116.8 48.0  ASN-2172   SER-2173  3.8 2.9 -12.5 23.4 100.2 68.2 1.8  SER-2173   CYS-2174  5.6 4.6 127.0 -95.7 83.9 88.4 20.5  CYS-2174   SER-2175  8.2 8.3 0.0 0.0 31.5 31.4 0.0  SER-2175   MET-2176  9.3 9.3 0.0 0.0 81.2 81.2 0.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees