Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-86   PRO-87  4.5 4.2 13.0 -8.0 79.0 93.9 -9.4  PRO-87   GLU-88  0.8 0.4 -73.1 10.9 38.6 41.2 112.8  GLU-88   ILE-89  3.5 3.4 20.6 -17.3 86.4 74.8 -22.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-186   PRO-187  5.8 4.3 -31.1 16.9 65.5 68.3 8.9  PRO-187   ALA-188  5.3 3.9 -11.5 -0.3 117.2 118.8 -6.4  ALA-188   VAL-189  6.3 4.9 24.8 -4.2 102.6 122.8 -18.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees