Sam-Dependent Methyltransferases

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-165   PHE-166  9.2 9.1 8.5 -16.5 167.0 167.2 52.7
 PHE-166   ALA-167  8.3 8.6 1.3 10.8 124.6 125.1 -38.0
 ALA-167   ASP-168  12.0 12.2 -4.7 10.1 56.0 44.5 -14.0
 ASP-168   ASP-169  13.1 13.2 -10.5 16.0 45.9 40.0 -19.8
 ASP-169   PHE-170  10.0 10.0 -18.6 7.6 32.6 39.0 84.1
 PHE-170   LEU-171  10.8 11.0 -17.3 10.3 60.6 63.4 55.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-188   ARG-189  20.5 20.3 -5.6 1.7 74.4 71.0 -0.3
 ARG-189   GLY-190  21.9 21.7 -9.2 36.5 129.4 126.5 150.0
 GLY-190   GLN-191  21.2 21.3 -36.2 29.3 74.5 87.8 -16.1
 GLN-191   PHE-192  19.0 18.4 -25.4 8.7 143.1 148.6 -103.8
 PHE-192   LEU-193  17.2 16.9 -5.4 7.4 129.1 123.6 0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-256   TRP-257  16.9 18.2 -34.7 36.9 116.4 119.9 -2.1
 TRP-257   ALA-258  19.5 20.6 -27.4 22.6 125.4 129.1 -22.6
 ALA-258   ASP-259  21.4 22.3 19.6 1.5 20.2 22.6 135.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-260   ASP-261  23.8 25.1 -21.2 17.2 114.7 113.3 -19.2
 ASP-261   ALA-262  24.3 24.8 -9.1 9.7 81.6 74.5 9.7
 ALA-262   VAL-263  21.3 21.3 -29.0 8.5 26.9 23.6 158.9
 VAL-263   ARG-264  22.4 22.1 -1.8 6.9 90.7 87.4 -24.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-283   LEU-284  12.5 12.2 1.1 10.1 118.3 122.0 -77.1
 LEU-284   ASP-285  10.2 10.1 28.6 -24.6 123.6 118.9 -30.5
 ASP-285   SER-286  8.8 8.0 -14.5 1.5 98.4 93.5 51.5
 SER-286   VAL-287  6.7 5.2 -1.6 13.5 145.7 136.8 147.9
 VAL-287   ILE-288  6.3 5.7 1.5 10.6 96.4 90.2 10.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-307   GLY-308  18.9 18.5 2.5 14.5 166.3 155.4 -123.3
 GLY-308   GLU-309  17.5 16.6 -28.6 11.1 72.1 73.4 -20.4
 GLU-309   HIS-310  14.7 14.2 3.4 -2.6 129.8 130.8 0.9
 HIS-310   ARG-311  11.9 11.1 -8.7 -25.5 11.4 26.3 271.8
 ARG-311   THR-312  11.9 11.5 -22.8 48.2 62.4 56.8 -116.7
 THR-312   ARG-313  9.9 9.9 -4.5 -3.6 37.8 44.6 55.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-334   ASP-335  5.8 6.1 -14.2 25.5 104.0 98.5 -55.7
 ASP-335   VAL-336  3.8 4.0 -9.3 4.1 75.2 79.3 -6.6
 VAL-336   TRP-337  0.3 0.6 -12.4 13.9 127.3 130.6 8.3
 TRP-337   ALA-338  3.5 3.8 -7.6 0.0 158.6 158.8 -56.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees