Topoisomerase V

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-416   GLU-417  20.9 20.4 -67.0 37.7 77.9 70.5 -11.3
 GLU-417   GLY-418  23.7 23.5 174.2 -166.9 125.3 99.9 82.4
 GLY-418   VAL-419  23.0 23.5 -1.6 0.5 43.2 66.4 4.9
 VAL-419   GLY-420  19.9 20.0 -7.2 14.3 18.9 16.5 -53.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-430   PHE-431  8.4 8.7 -8.4 7.4 130.4 130.2 -22.5
 PHE-431   GLY-432  5.5 5.9 18.3 -16.8 106.0 109.3 63.5
 GLY-432   ASN-433  3.0 3.4 13.4 -22.6 94.1 97.2 -50.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-446   GLU-447  14.6 14.4 -0.1 -11.9 127.5 124.7 -122.5
 GLU-447   LYS-448  16.4 15.8 19.1 -11.2 33.8 37.1 107.1
 LYS-448   LEU-449  13.5 12.9 -13.1 12.0 132.2 136.7 -2.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-453   GLY-454  18.5 18.3 -2.6 3.1 84.6 88.8 -86.4
 GLY-454   VAL-455  19.8 19.9 21.9 -15.5 24.0 34.8 -10.3
 VAL-455   GLY-456  18.7 19.1 -10.5 36.3 128.1 137.4 271.1
 GLY-456   GLU-457  21.7 22.2 3.4 2.1 39.4 29.5 -37.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees