Glutamate Receptor, Ionotropic Kainate 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-107   LEU-108  7.6 6.4 23.4 -8.2 112.4 116.7 -33.8  LEU-108   GLY-109  4.5 3.0 -9.3 18.8 136.1 135.5 13.8  GLY-109   ILE-110  2.9 2.3 -54.1 25.7 60.7 65.7 44.0  ILE-110   SER-111  4.8 4.5 -0.7 -9.9 58.8 67.0 17.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-208   GLY-209  12.9 13.0 24.5 -35.3 100.7 91.8 -13.2  GLY-209   LEU-210  11.5 10.5 6.2 15.6 104.8 119.0 -30.1  LEU-210   ILE-211  8.1 7.3 0.6 13.3 155.6 155.5 -37.1  ILE-211   ASP-212  7.4 7.6 -171.0 143.3 68.6 43.6 16.0  ASP-212   SER-213  4.5 4.6 138.6 -105.2 73.0 63.1 50.2  SER-213   LYS-214  4.9 3.5 -6.6 11.9 77.3 72.8 11.1  LYS-214   GLY-215  4.0 3.3 13.2 -2.5 41.0 42.4 22.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  TRP-250   TRP-251  8.1 8.3 -2.1 -4.4 96.4 92.2 -0.3  TRP-251   ARG-252  4.8 5.2 30.9 14.3 147.3 149.4 -101.7  ARG-252   GLY-253  5.3 5.8 -40.7 -48.0 53.7 71.4 133.6  GLY-253   ASN-254  2.4 2.9 -148.1 45.4 25.5 63.3 210.1  ASN-254   GLY-255  3.0 5.3 24.0 92.2 108.7 114.7 -108.0  GLY-255   CYS-256  5.6 4.9 16.3 -144.0 71.8 45.5 -172.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees