Dual Specificity Mitogen-Activated Protein Kinase Kinase 6

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-71   HIS-72  4.1 5.5 7.8 -6.4 25.8 24.5 4.8
 HIS-72   VAL-73  3.1 5.4 29.5 -16.5 85.9 81.5 -0.9
 VAL-73   PRO-74  6.8 8.6 -7.4 -2.4 107.7 103.1 -0.1
 PRO-74   SER-75  8.0 10.3 12.3 -6.4 136.0 139.2 -5.3
 SER-75   GLY-76  8.0 10.6 1.5 -7.6 149.2 143.7 6.1
 GLY-76   GLN-77  7.4 10.2 -1.5 2.8 49.6 48.0 -0.2
 GLN-77   ILE-78  4.6 7.7 15.4 -18.8 93.1 98.0 -2.3

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees