Proto-Oncogene Tyrosine-Protein Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-235   ALA-236  23.7 24.1 -0.1 0.0 89.7 94.7 0.1
 ALA-236   PRO-237  20.6 20.9 0.1 0.2 155.0 145.7 -0.2
 ASP-252   LYS-253  8.9 9.3 -1.7 -72.7 121.7 77.6 -12.3
 LYS-253   TRP-254  5.9 5.7 55.5 1.9 34.2 34.9 25.1
 TRP-254   GLU-255  7.0 6.9 -0.6 0.1 88.6 89.1 -0.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees