Elongation Factor 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Elongation Factor 2
  Conformer 1
(PDB)
2e1r (A)
  Conformer 2
(PDB)
2npf (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 448 0.68   5 - 111   119 - 482
2 361 0.69   112 - 118   483 - 840

Sequence


           ______________________________________________________________________________________________111____118________________ 
 2e1r(A) : MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKeRGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEG 
         :                                                                                                                          
 2npf(B) : **AFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISA----gITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLID-----dFSSEVTAALRVTDGALVVVDTIEG 
           ______________________________________________________________________________________________111____118________________ 

           ________________________________________________________________________________________________________________________ 
 2e1r(A) : VCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRLWGDSFFNPKT 
         :                                                                                                                          
 2npf(B) : VCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRLWGDSFFNPKT 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2e1r(A) : KKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDP 
         :                                                                                                                          
 2npf(B) : KKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDP 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________481_____________ 
 2e1r(A) : KADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVE 
         :                                                                                                                          
 2npf(B) : KADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVE 
           ________________________________________________________________________________________________________481_____________ 

           ________________________________________________________________________________________________________________________ 
 2e1r(A) : VKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKA 
         :                                                                                                                          
 2npf(B) : VKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKA 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2e1r(A) : RARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQ 
         :                                                                                                                          
 2npf(B) : RARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQ 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________________________________________________             
 2e1r(A) : CPEQAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL             
         :                                                                                                                          
 2npf(B) : CPEQAVGGIYSVLNKKRGQVVSEEQ----pLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL             
           ____________________________________________________________________________________________________________             

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
7.2
Translation
(A)
-0.8
Closure
(%)
78.3
Bending Residues
( green )
  111 - 116
  118 - 119
  481 - 483
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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