3-Isopropylmalate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 3-Isopropylmalate Dehydrogenase
  Conformer 1
(PDB)
1osj (A)
  Conformer 2
(PDB)
1idm  
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 185 0.82   3 - 99   251 - 259   263 - 343
2 154 0.39   100 - 250   260 - 262

Sequence


           _________________________________________________________________________________________________99_____________________ 
 1osj(A) : MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVEEAEAVLLGSVGGPKWDGLPRKIRPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKE 
         :                                                                                                                          
 1idm    : MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVEEAEAVLLGSVGGPKWG--TGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLKE 
           _________________________________________________________________________________________________97_____________________ 

           ________________________________________________________________________________________________________________________ 
 1osj(A) : EIARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFELARKRRKHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFG 
         :                                                                                                                          
 1idm    : EIARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFG 
           ________________________________________________________________________________________________________________________ 

           ___246__________259______________________________________________________________________________________                
 1osj(A) : DILSDLASVLPGSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHAFGLVELARKVEDAVAKALLETPPPDLGGSAGTEAFTATVLRHLA                
         :                                                                                                                          
 1idm    : DILSDLASVLPGSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHAFGLVELARKVEDAVAKALLETPPPDLGGSAGTEAFTATVLRHLA                
           ___244__________257______________________________________________________________________________________                

Morph

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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
15.3
Translation
(A)
-0.1
Closure
(%)
86.5
Bending Residues
( green )
  99 - 104
  246 - 255
  259 - 263
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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