Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		7vjl (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 171 1.68   541 - 545   564 - 761
2 89 0.8   467 - 540   546 - 563

Sequence


           ________________________________________________________________________538____545_______________563____________________ 
 3gqi(A) : ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEF 
         :                                                                                                                          
 7vjl(B) : DLPLDPLWEFPRDRLVLGKPLG---fGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPg--- 
           ________________________________________________________________________527____534_______________552____________________ 

           ________________________________________________________________________________________________________________________ 
 3gqi(A) : SFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP 
         :                                                                                                                          
 7vjl(B) : ---P-------LSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFG-----------------pVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________                                                         
 3gqi(A) : VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                         
         :                                                                                                                          
 7vjl(B) : VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEE*****                                                         
           ________________________________________________________________                                                         

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		23.8
Translation
(A) 		0.1
Closure
(%) 		99.4
Bending Residues
( green ) 		  538 - 541
  545 - 546
  563 - 564
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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