Immunoglobulin 48G7 Germline Fab

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Immunoglobulin 48G7 Germline Fab
  Conformer 1
(PDB) 		1gaf (L)
  Conformer 2
(PDB) 		1gpo (L)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 104 0.66   106 - 209
2 103 1.2   3 - 105

Sequence


           ___________________________________________________________________________________________________________105__________ 
 1gaf(L) : DIQMTQSPSSLSASLGERVSLTCRASQEI-----NGYLGWLQQKPDGTIKRLIYAASTLHSGVPKRFSGSRSGSDYSLTISSLESEDFADYYCLQYASYPRTFGGGTKVEIKRTVAAPSV 
         :                                                                                                                          
 1gpo(L) : DIELTQSPATLSVTPGNSVSISCRASQSLVNEDGNTYLFWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSGTDFTLSINSVETEDLAVYFCQQITDWPFTFGGGTKLEIKRADAAPTV 
           ___________________________________________________________________________________________________________110__________ 

           ___________________________________________________________________________________________________                      
 1gaf(L) : FIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC                      
         :                                                                                                                          
 1gpo(L) : SIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNR***                      
           ___________________________________________________________________________________________________                      

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		28.3
Translation
(A) 		-0.6
Closure
(%) 		77.3
Bending Residues
( green ) 		  105 - 106
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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