DynDom - Protein Domain Motions

Glycogen [Starch] Synthase Isoform 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Glycogen [Starch] Synthase Isoform 2
Conformer 1 (PDB)	3nb0 (C)
Conformer 2 (PDB)	4kq1 (C)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	332	0.43	200 - 208 211 - 214 278 - 596
2	302	0.49	4 - 199 209 - 210 215 - 277 597 - 637

Sequence

`________________________________________________________________________________________________________________________` `3nb0(C) : SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGD` `:` `4kq1(C) : SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGD` `________________________________________________________________________________________________________________________` `___________________________________________________________________________199_____207___213____________________________` `3nb0(C) : LWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSA` `:` `4kq1(C) : LWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSA` `___________________________________________________________________________199_____207___213____________________________` `_________________________________277____________________________________________________________________________________` `3nb0(C) : DVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKN` `:` `4kq1(C) : DVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKN` `_________________________________277____________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3nb0(C) : NSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFL` `:` `4kq1(C) : NSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFL` `________________________________________________________________________________________________________________________` `___________________________________________________________________________________________________________591__________` `3nb0(C) : NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNATEALSDLLDWKR` `:` `4kq1(C) : NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNATEALSDLLDWKR` `___________________________________________________________________________________________________________591__________` `______________________________________________` `3nb0(C) : MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALAGGKKLKVA` `:` `4kq1(C) : MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA********` `______________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	9.5
Translation (A)	-0.1
Closure (%)	98.0
Bending Residues ( green )	199 - 200 207 - 211 213 - 215 277 - 278 591 - 597
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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