Lactose Permease

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Lactose Permease
  Conformer 1
(PDB) 		2v8n (A)
  Conformer 2
(PDB) 		4oaa (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 194 1.37   208 - 401
2 186 1.88   6 - 207

Sequence


           ________________________________________________________________________________________________________________________ 
 2v8n(A) : MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNA 
         :                                                                                                                          
 4oaa(B) : ***LKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTWIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNA 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________207_________________________________________________ 
 2v8n(A) : GAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFD 
         :                                                                                                                          
 4oaa(B) : GAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTD----------------aFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFD 
           ____________________________________________________________________207_________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2v8n(A) : QQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQL 
         :                                                                                                                          
 4oaa(B) : QQFANFFTSFFATGEQGTRVFWYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQL 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________                                                                
 2v8n(A) : AMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA                                                                
         :                                                                                                                          
 4oaa(B) : AMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLR*******                                                                
           _________________________________________________________                                                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		30.2
Translation
(A) 		1.2
Closure
(%) 		100.0
Bending Residues
( green ) 		  207 - 215
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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