DynDom - Protein Domain Motions

Phosphomannomutase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphomannomutase
Conformer 1 (PDB)	1k35 (A)
Conformer 2 (PDB)	2fkm (X)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	366	0.59	12 - 366 396 - 412 417 - 419
2	75	0.48	367 - 395 413 - 416 420 - 461

Sequence

`________________________________________________________________________________________________________________________` `1k35(A) : LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVG-vPTPVLYYAANVLEGKSGV-lTG-hNPPDYNGFKIVVAGETLAN` `:` `2fkm(X) : *PASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGDHNPPDYNGFKIVVAGETLAN` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `1k35(A) : EQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIA-aKP-kVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRV` `:` `2fkm(X) : EQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRV` `________________________________________________________________________________________________________________________` `___________________________________________________________________________________________________________________366__` `1k35(A) : GVVTNTGTIIYPDRLL-lFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPV-wKTGHSLIKKK-kETGALLAGE-sGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFP` `:` `2fkm(X) : GVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFP` `___________________________________________________________________________________________________________________366__` `_______________________394_______________412_416_______________________________________________` `1k35(A) : SDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF` `:` `2fkm(X) : SDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF` `_______________________394_______________412_416_______________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	8.3
Translation (A)	0.5
Closure (%)	89.2
Bending Residues ( green )	366 - 367 394 - 396 412 - 413 416 - 417 419 - 420
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file

Download