DynDom - Protein Domain Motions

Phosphoenolpyruvate-Protein Phosphotransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphoenolpyruvate-Protein Phosphotransferase
Conformer 1 (PDB)	2hwg (B)
Conformer 2 (PDB)	1zym (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	128	1.36	19 - 148
2	103	1.2	5 - 18 149 - 240

Sequence

`_______________18_______________________________________________________________________________________________________` `2hwg(B) : ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHI-lLEDEELEQEIIALIKDKH-tADAAAHEVIEGQASALEELDDE` `:` `1zym(A) : SGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDE` `_______________18_______________________________________________________________________________________________________` `______________________146_______________________________________________________________________________________________` `2hwg(B) : YLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTS-tSI-aRSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDK-rA` `:` `1zym(A) : YLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRA` `______________________146_______________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hwg(B) : VQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFdRDALPTEEEQFAAYKAVAEACGSQAVIVRTdIGGDKELPYnFPKEENPFLGWRAIRIAd` `:` `1zym(A) : VQEQVASE*************************************************************************************************************` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hwg(B) : RREILRDQLRAILRASAFGKLRIfPiISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVvETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDiSHLYQPsPSVLNLIKQVID` `:` `1zym(A) : ********************************************************************************************************************` `________________________________________________________________________________________________________________________` `_______________________________________________________________________________` `2hwg(B) : ASHAEGKWTGcGELAGDERATLLLLGgLDEFSsAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELtLVNKFIEEKT` `:` `1zym(A) : *****************************************************************************` `_______________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	66.5
Translation (A)	1.0
Closure (%)	91.3
Bending Residues ( green )	18 - 21 146 - 152
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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