Gdp-Mannose-Dependent Alpha-(1-2)-Phosphatidylinositol Mannosyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Gdp-Mannose-Dependent Alpha-(1-2)-Phosphatidylinositol Mannosyltransferase
  Conformer 1
(PDB) 		2gej (A)
  Conformer 2
(PDB) 		4nc9 (B)
  Window Length 13
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 321 4.11   7 - 132   158 - 158   160 - 367
2 20 7.31   133 - 157   159 - 159

Sequence


           ________________________________________________________________________________________________________________________ 
 2gej(A) : **MRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAV------fGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKS 
         :                                                                                                                          
 4nc9(B) : GAMRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAVPvARLRFGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKS 
           ________________________________________________________________________________________________________________________ 

           ____131_______________________157_______________________________________________________________________________________ 
 2gej(A) : LTLSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGH 
         :                                                                                                                          
 4nc9(B) : LTLSVFQGILRPYH------iAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGH 
           ____131_______________________157_______________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2gej(A) : LRFLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVS 
         :                                                                                                                          
 4nc9(B) : LRFLGQVDDATKASAMRSADVYCAPHL--eSFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVS 
           ________________________________________________________________________________________________________________________ 

           _________                                                                                                                
 2gej(A) : GAGIKVQVS                                                                                                                
         :                                                                                                                          
 4nc9(B) : GAGIKVQVS                                                                                                                
           _________                                                                                                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		111.1
Translation
(A) 		4.0
Closure
(%) 		93.7
Bending Residues
( green ) 		  131 - 133
  157 - 166
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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