Thermolysin (E.C.3.4.24.27)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Thermolysin (E.C.3.4.24.27)
  Conformer 1
(PDB) 		1tmn (E)
  Conformer 2
(PDB) 		1npc  
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 209 0.66   5 - 7   32 - 39   79 - 98   113 - 120   137 - 193   202 - 314
2 103 0.47   3 - 4   8 - 31   40 - 78   99 - 112   121 - 136   194 - 201

Sequence


           ___4__7_______________________31_34__________________________________________78_________________97____________112_____12 
 1tmn(E) : ITGTSTVGVGRGVLGDQKNINTTYS-TYYYLQDNTRGDGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSE 
         :                                                                                                                          
 1npc    : VTGTNKVGTGKGVLGDTKSLNTTLSGSSYYLQDNTRGATIFTYDAKNRSTLPGTLWADADNVFNAAYDAAAVDAHYYAGKTYDYYKATFNRNSINDAGAPLKSTVHYGSNYNNAFWNGSQ 
           ___4__7_______________________32_35__________________________________________79_________________98____________113_____12 

           0_____________136______________________________________________________193____200_______________________________________ 
 1tmn(E) : MVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINK 
         :                                                                                                                          
 1npc    : MVYGDGDGVTFTSLSGGIDVIGHELTHAVTENSSNLIYQNESGALNEAISDIFGTLVEFYDNRNPDWEIGEDIYTPGKAGDALRSMSDPTKYGDPDHYSKRYTGSSDNGGVHTNSGIINK 
           1_____________137______________________________________________________194____201_______________________________________ 

           _____________________________________________________________________________                                            
 1tmn(E) : AAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK                                            
         :                                                                                                                          
 1npc    : QAYLLANGGTHYGVTVTGIGKDKLGAIYYRANTQYFTQSTTFSQARAGAVQAAADLYGANSAEVAAVKQSFSAVGVN                                            
           _____________________________________________________________________________                                            

Morph
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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		4.6
Translation
(A) 		0.2
Closure
(%) 		99.3
Bending Residues
( green ) 		  4 - 5
  7 - 8
  31 - 32
  34 - 40
  78 - 79
  97 - 99
  112 - 113
  120 - 121
  136 - 137
  193 - 197
  200 - 202
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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