Tight Junction Protein Zo-1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Tight Junction Protein Zo-1
  Conformer 1
(PDB) 		3lh5 (A)
  Conformer 2
(PDB) 		3kfv (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 143 1.31   642 - 798
2 80 2.35   519 - 641   799 - 800

Sequence


           _________________________________________________________________________________________________641____________________ 
 3lh5(A) : GDSFYIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYVQT-----------KFPAYERVVLREAGFLRPVTIFGPIADVAREKL 
         :                                                                                                                          
 3kfv(A) : *DSFYIRTHFELEPSPPSGLGFTRGDVFHVLDT-------hWLAVR-gRDLREQERGIIPNQSRAEQLASLEAAQRAeDLSALTRQGRYPPYERVVLREASFKRPVVILGPVADIAqKLT 
           _________________________________________________________________________________________________629____________________ 

           ________________________________________________________________________________________________________________________ 
 3lh5(A) : AREEPDIYQIAKSEPRDAGTDQgIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYG 
         :                                                                                                                          
 3kfv(A) : A--EpDQFEIAETV---------iIKLDTVRVIAEKDKHALLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALRQWLAPASRRSTRRLYAQAQKLRKHSSHLFTATIPLNGTSDTWYQ 
           ________________________________________________________________________________________________________________________ 

           ___________798_____                                                                                                      
 3lh5(A) : ALKEAIQQQQNQLVWVSEG                                                                                                      
         :                                                                                                                          
 3kfv(A) : ELKAIIREQQTRPIWTAE*                                                                                                      
           ___________782_____                                                                                                      

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		33.5
Translation
(A) 		-2.1
Closure
(%) 		20.4
Bending Residues
( green ) 		  641 - 642
  798 - 799
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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