DynDom - Protein Domain Motions

Udp-Galactose 4-Epimerase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Udp-Galactose 4-Epimerase
Conformer 1 (PDB)	1ek6 (B)
Conformer 2 (PDB)	1i3n (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	196	0.69	4 - 131 136 - 136 149 - 150 152 - 185 191 - 193 244 - 269 343 - 344
2	145	0.55	132 - 135 137 - 148 151 - 151 186 - 190 194 - 243 270 - 342

Sequence

`________________________________________________________________________________________________________________________` `1ek6(B) : AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA` `:` `1i3n(A) : AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAMGESVQKPLDYYRVNLTGTIQLLEIMKA` `________________________________________________________________________________________________________________________` `_______131_135__________148__________________________________185__190__________________________________________________2` `1ek6(B) : HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDY` `:` `1i3n(A) : HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDY` `_______131_135__________148__________________________________185__190__________________________________________________2` `43_______________________269______________________________________________________________________342______` `1ek6(B) : IHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGT**` `:` `1i3n(A) : IHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA` `43_______________________269______________________________________________________________________342______`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	7.2
Translation (A)	-0.2
Closure (%)	99.8
Bending Residues ( green )	131 - 132 135 - 137 148 - 152 185 - 186 190 - 191 193 - 194 243 - 244 269 - 270 342 - 344
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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