Unconventional Myosin-Va

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Unconventional Myosin-Va
  Conformer 1
(PDB) 		7plu (A)
  Conformer 2
(PDB) 		1w7j (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 219 1.74   7 - 151   157 - 198   226 - 228   430 - 432   441 - 441   658 - 690
2 158 0.93   152 - 156   224 - 225   229 - 238   433 - 440   442 - 473   490 - 568   636 - 657
3 235 0.96   199 - 223   239 - 429   574 - 592
4 107 0.71   474 - 487   698 - 790

Sequence


           ________________________________________________________________________________________________________________________ 
 7plu(A) : ***ELYTKYARVWIPDPEEVWKSAELLKDYKP--kVLQLRLEEGKDLEYCLDP----lPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGE 
         :                                                                                                                          
 1w7j(A) : AASELYTKYARVWIPDPEEVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGE 
           ________________________________________________________________________________________________________________________ 

           ___________________________151____________________________________________198_______________________224_228______237____ 
 7plu(A) : DIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA--aNVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 
         :                                                                                                                          
 1w7j(A) : DIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 
           ___________________________151____________________________________________198_______________________224_228______237____ 

           ________________________________________________________________________________________________________________________ 
 7plu(A) : YLLEKSRVVFQAEEERNYHIFYQLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDPLTIFC 
         :                                                                                                                          
 1w7j(A) : YLLEKSRVVFQAEEERNYHIFYQLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDPLTIFC 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________424_____432_____440______________________________473________ 
 7plu(A) : DLMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHSTVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 
         :                                                                                                                          
 1w7j(A) : DLMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHSTVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 
           ____________________________________________________________424_____432_____440______________________________473________ 

           ___487______________________________________________________________________________568_____________________592_________ 
 7plu(A) : IPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQDsKEHKK 
         :                                                                                                                          
 1w7j(A) : IPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQ------k 
           ___487______________________________________________________________________________568_____________________592_________ 

           ____________________657______________________________690________________________________________________________________ 
 7plu(A) : TVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAG 
         :                                                                                                                          
 1w7j(A) : TVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAG 
           ____________________657______________________________690________________________________________________________________ 

           ______________________________________                                                                                   
 7plu(A) : QVAYLEKIRADKLRAACIRIQKTIRGWLMRKKYMRMRR                                                                                   
         :                                                                                                                          
 1w7j(A) : QVAYLEKIRADKLRAACIRIQKTIRGWLMRKKYMRMRR                                                                                   
           ______________________________________                                                                                   

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 9.9 -0.4 44.8   151 - 157   224 - 226   228 - 229   432 - 433   440 - 442   657 - 658 Bending Region Analysis
1 3 25.7 0.1 22.0   198 - 199   424 - 430 Bending Region Analysis
1 4 25.8 -1.4 77.4   690 - 698 Bending Region Analysis
2 3 19.2 -0.2 15.0   223 - 225   237 - 239   568 - 574   592 - 636 Bending Region Analysis
2 4 18.3 -0.4 76.3   473 - 474   487 - 490 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 4

Conformer 2 Contact:
Residue 4 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 2 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 2

Movement classification: Hinge

Conformer 1 Contact:
Residue 2 ———› Residue 4

Conformer 2 Contact:
Residue 4 ———› Residue 2

Movement classification:

No Contacts

PyMOL Script

Download and extract PyMOL PML script file Download