DynDom - Protein Domain Motions

Gamma-Aminobutyric Acid Type B Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Gamma-Aminobutyric Acid Type B Receptor Subunit 2
Conformer 1 (PDB)	4mqe (B)
Conformer 2 (PDB)	4ms3 (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	228	1.04	55 - 176 178 - 178 319 - 426 437 - 438
2	168	0.4	177 - 177 179 - 318 427 - 436 439 - 465

Sequence

`________________________________________________________________________________________________________________________` `4mqe(B) : ***SPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKY` `:` `4ms3(B) : PPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKY` `________________________________________________________________________________________________________________________` `____176_________________________________________________________________________________________________________________` `4mqe(B) : PYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSW` `:` `4ms3(B) : PYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSW` `____176_________________________________________________________________________________________________________________` `___________________318__________________________________________________________________________________________________` `4mqe(B) : WEQsRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHAS-----iQDFNYTDHTLGRIILNAMNETNFFGVTGQVV` `:` `4ms3(B) : WE---cLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVV` `___________________318__________________________________________________________________________________________________` `_______426___432___________________________________` `4mqe(B) : FRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDD` `:` `4ms3(B) : FRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDD` `_______426___432___________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	8.6
Translation (A)	0.1
Closure (%)	23.3
Bending Residues ( green )	176 - 181 318 - 319 426 - 427 432 - 439
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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