Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Subunit 2
  Conformer 1
(PDB) 		1fto (B)
  Conformer 2
(PDB) 		1mqg (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 173 0.55   7 - 109   115 - 121   192 - 203   205 - 214   216 - 256
2 77 0.71   110 - 114   122 - 191   204 - 204   215 - 215

Sequence


           ________________________________________________________________________________________________________109__114___120__ 
 1fto(B) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1mqg(B) : NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
           ________________________________________________________________________________________________________109__114___120__ 

           __________________________________________________________________191_________203_______213_____________________________ 
 1fto(B) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
         :                                                                                                                          
 1mqg(B) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
           __________________________________________________________________191_________203_______213_____________________________ 

           ____________________                                                                                                     
 1fto(B) : EQGLLDKLKNKWWYDKGEC*                                                                                                     
         :                                                                                                                          
 1mqg(B) : EQGLLDKLKNKWWYDKGECG                                                                                                     
           ____________________                                                                                                     

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		15.6
Translation
(A) 		-0.1
Closure
(%) 		85.2
Bending Residues
( green ) 		  109 - 110
  114 - 115
  120 - 124
  191 - 195
  203 - 205
  213 - 218
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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