DynDom - Protein Domain Motions

Glycogen [Starch] Synthase Isoform 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Glycogen [Starch] Synthase Isoform 2
Conformer 1 (PDB)	3o3c (A)
Conformer 2 (PDB)	3nb0 (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	587	1.12	4 - 381 415 - 637
2	20	0.5	382 - 401

Sequence

`________________________________________________________________________________________________________________________` `3o3c(A) : SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGD` `:` `3nb0(A) : SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGD` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3o3c(A) : LWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASG--dFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSA` `:` `3nb0(A) : LWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSA` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3o3c(A) : DVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQ-------lHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKN` `:` `3nb0(A) : DVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKN` `________________________________________________________________________________________________________________________` `_________________381________________400_________________________________________________________________________________` `3o3c(A) : NSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYP-------------eLLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFL` `:` `3nb0(A) : NSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFL` `_________________381________________400_________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3o3c(A) : NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDL-----aKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTAAQAINQRNRTERLSDLLDWKR` `:` `3nb0(A) : NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNATEALSDLLDWKR` `________________________________________________________________________________________________________________________` `______________________________________` `3o3c(A) : MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA` `:` `3nb0(A) : MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA` `______________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	22.1
Translation (A)	-0.5
Closure (%)	69.6
Bending Residues ( green )	381 - 382 400 - 415
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

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