Isocitrate Dehydrogenase [Nadp] Cytoplasmic

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Isocitrate Dehydrogenase [Nadp] Cytoplasmic
  Conformer 1
(PDB) 		3inm (A)
  Conformer 2
(PDB) 		3map (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 237 0.86   6 - 118   285 - 408
2 152 1.74   119 - 284

Sequence


           _______________________________________________________________________________________________________________116______ 
 3inm(A) : *KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 
         :                                                                                                                          
 3map(A) : KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 
           _______________________________________________________________________________________________________________116______ 

           ________________________________________________________________________________________________________________________ 
 3inm(A) : GWVKPIIIGHHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 
         :                                                                                                                          
 3map(A) : GWVKPIIIGHHA-----rATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 
           ________________________________________________________________________________________________________________________ 

           _______________________________________284______________________________________________________________________________ 
 3inm(A) : KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 
         :                                                                                                                          
 3map(A) : KIWYEHRLIDDMVAQAMKSEGGFIWACKN---------vAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 
           _______________________________________284______________________________________________________________________________ 

           ___________________________________________________                                                                      
 3inm(A) : SIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA***                                                                      
         :                                                                                                                          
 3map(A) : SIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK                                                                      
           ___________________________________________________                                                                      

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		29.0
Translation
(A) 		0.2
Closure
(%) 		77.7
Bending Residues
( green ) 		  116 - 123
  284 - 288
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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