Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		4j99 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 187 1.14   534 - 538   541 - 545   564 - 759
2 88 1.01   466 - 533   539 - 540   546 - 563

Sequence


           ____________________________________________________________________533__538____545_______________563___________________ 
 3gqi(A) : *ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 
         :                                                                                                                          
 4j99(A) : YELPEDPKWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP---- 
           ____________________________________________________________________536__541____548_______________566___________________ 

           ________________________________________________________________________________________________________________________ 
 3gqi(A) : FSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV 
         :                                                                                                                          
 4j99(A) : -----------qMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDIN--dYYKTnGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________                                                        
 3gqi(A) : PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                        
         :                                                                                                                          
 4j99(A) : PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT********                                                        
           _________________________________________________________________                                                        

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		10.7
Translation
(A) 		0.0
Closure
(%) 		67.7
Bending Residues
( green ) 		  533 - 534
  538 - 541
  545 - 546
  563 - 564
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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