Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Subunit 2
  Conformer 1
(PDB) 		1fto (A)
  Conformer 2
(PDB) 		2i0b (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 143 1.27   7 - 109   197 - 198   217 - 254
2 106 1.58   110 - 196   199 - 216   255 - 258

Sequence


           _______________________________________________________________________________________________________109______________ 
 1fto(A) : *TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIES 
         :                                                                                                                          
 2i0b(A) : RSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREEVIDFSKPFMTLGISILYRKGTPIDS 
           _______________________________________________________________________________________________________109______________ 

           ______________________________________________________________________196_________________216___________________________ 
 1fto(A) : AEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNE 
         :                                                                                                                          
 2i0b(A) : ADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITLAILKLQE 
           ______________________________________________________________________194_________________213___________________________ 

           ________254_______                                                                                                       
 1fto(A) : QGLLDKLKNKWWYDKGEC                                                                                                       
         :                                                                                                                          
 2i0b(A) : QGKLHMMKEKWWRGNG-C                                                                                                       
           ________251_______                                                                                                       

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		24.8
Translation
(A) 		0.2
Closure
(%) 		91.9
Bending Residues
( green ) 		  109 - 110
  196 - 199
  216 - 217
  254 - 255
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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