Mitogen-Activated Protein Kinase 14

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mitogen-Activated Protein Kinase 14
  Conformer 1
(PDB) 		2y8o (A)
  Conformer 2
(PDB) 		1p38 (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 273 0.99   61 - 87   91 - 105   108 - 349
2 59 0.53   7 - 60   88 - 90   106 - 107

Sequence


           _______________________________________________________60_________________________87_90____________105__________________ 
 2y8o(A) : ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLT 
         :                                                                                                                          
 1p38(A) : ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLT 
           _______________________________________________________60_________________________87_90____________105__________________ 

           ________________________________________________________________________________________________________________________ 
 2y8o(A) : DDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDSELKILDFGLAR-----------tRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPG 
         :                                                                                                                          
 1p38(A) : DDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPG 
           ________________________________________________________________________________________________________________________ 

           _______________________________________________________________________________________________________________          
 2y8o(A) : AELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL*          
         :                                                                                                                          
 1p38(A) : AELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLD          
           _______________________________________________________________________________________________________________          

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		5.7
Translation
(A) 		-0.1
Closure
(%) 		80.7
Bending Residues
( green ) 		  60 - 61
  87 - 88
  90 - 91
  105 - 110
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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