DynDom - Protein Domain Motions

RNA Helicase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	RNA Helicase
Conformer 1 (PDB)	1cu1 (A)
Conformer 2 (PDB)	1a1v (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	288	1.05	192 - 330 435 - 446 484 - 622
2	137	1.06	331 - 434 447 - 483

Sequence

`________________________________________________________________________________________________________________________` `1cu1(A) : GSVVIVGRIILSGSGSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYL` `:` `1a1v(A) : **********************************************************************************************************************` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `1cu1(A) : VTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVL` `:` `1a1v(A) : *******************************************************************************PPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVL` `________________________________________________________________________________________________________________________` `_____________________________________________________________________________________________________330________________` `1cu1(A) : VLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGE` `:` `1a1v(A) : VLNPSVAATLGFGAYMSKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGG-sGGAYDIIICDECHSTDATSILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSTTGE` `_____________________________________________________________________________________________________330________________` `_____________________________________________________________________________________434_________446____________________` `1cu1(A) : IPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTG` `:` `1a1v(A) : IPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTSGDVVVVATDAL---fTGDFDSVIDCNT-vTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTG` `_____________________________________________________________________________________434_________446____________________` `____________481_________________________________________________________________________________________________________` `1cu1(A) : RGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLI` `:` `1a1v(A) : RGKPGIYRFVAPGERPSGMFDSSVLCECYDAG-aWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMWKCLI` `____________481_________________________________________________________________________________________________________` `_____________________________________________` `1cu1(A) : RLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT` `:` `1a1v(A) : RLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMTCMS*****` `_____________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	12.0
Translation (A)	0.7
Closure (%)	81.4
Bending Residues ( green )	330 - 331 434 - 435 446 - 447 481 - 484
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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