DynDom - Protein Domain Motions

Protein (Arrestin)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Protein (Arrestin)
Conformer 1 (PDB)	1cf1 (C)
Conformer 2 (PDB)	4j2q (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	177	2.9	177 - 295 299 - 319 321 - 322 324 - 358
2	165	2.21	12 - 176 296 - 298 320 - 320 323 - 323

Sequence

`________________________________________________________________________________________________________________________` `1cf1(C) : APNHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYL` `:` `4j2q(B) : *HVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYL` `________________________________________________________________________________________________________________________` `_______________________________________________176______________________________________________________________________` `1cf1(C) : PCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTN` `:` `4j2q(B) : PCSVMLQPAPQDVGKSCGVDFEIKAFATHSTD-----iPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTN` `_______________________________________________176______________________________________________________________________` `______________________________________________295____________________318________________________________________________` `1cf1(C) : VVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHPQPEDPDdE` `:` `4j2q(B) : VVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHPQP**` `______________________________________________295____________________318________________________________________________` `____________________` `1cf1(C) : NFVFEEFARQNLKDAGEYKE` `:` `4j2q(B) : ******************` `____________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	21.9
Translation (A)	-1.7
Closure (%)	35.2
Bending Residues ( green )	176 - 177 295 - 302 318 - 324
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file