DynDom - Protein Domain Motions

Tryptophan Synthase Beta Chain 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Tryptophan Synthase Beta Chain 1
Conformer 1 (PDB)	1wdw (L)
Conformer 2 (PDB)	1v8z (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	44	0.54	3 - 7 11 - 14 188 - 188 265 - 292 297 - 297 300 - 304
2	218	0.3	8 - 10 22 - 30 40 - 42 47 - 84 92 - 95 182 - 187 189 - 192 197 - 264 293 - 296 298 - 299 305 - 381
3	114	0.38	18 - 21 31 - 39 43 - 46 85 - 91 96 - 181 193 - 196

Sequence

`______7_10__14____20_________________39_42__46____________________________________84_____91__95_________________________` `1wdw(L) : MWFGEFGGQYVPETLIEPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKIYLKREDLVHGGAHKTNNAIGQALLAKFMGKTRLIAETGAGQHGVATAMAGAL` `:` `1v8z(B) : MWFGEFGGQYVPETLIEPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKIYLKREDLVHGGAHKTNNAIGQALLAKFMGKTRLIAETGAGQHGVATAMAGAL` `______7_10__14____20_________________39_42__46____________________________________84_____91__95_________________________` `__________________________________________________________181__186___192_196____________________________________________` `1wdw(L) : LGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFV` `:` `1v8z(B) : LGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFV` `__________________________________________________________181__186___192_196____________________________________________` `_____________________264_________________________292_________304________________________________________________________` `1wdw(L) : NDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVFHGMLSYFLQDEEGQIKPTHSIAPGLDYPGVGPEHAYLKKIQRAEYVTVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEM` `:` `1v8z(B) : NDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVFHGMLSYFLQDEEGQIKPTHSIAPGLDYPGVGPEHAYLKKIQRAEYVTVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEM` `_____________________264_________________________292_________304________________________________________________________` `___________________________` `1wdw(L) : SRDEIIIVNLSGRGDKDLDIVLKVS**` `:` `1v8z(B) : SRDEIIIVNLSGRGDKDLDIVLKVSGN` `___________________________`

Morph

Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

Show console

play backwards

pause

play forwards

Domain Pairs

Fixed Domain	Moving Domain	Rotation Angle	Translation (A)	Closure	Bending Residues
1	2	5.2	0.1	34.9	7 - 8 10 - 11 186 - 190 264 - 265 292 - 301 304 - 305	Bending Region Analysis
1	3	10.6	0.1	99.8	14 - 18	Bending Region Analysis
3	2	5.3	0.0	51.6	20 - 31 39 - 40 42 - 43 46 - 48 84 - 85 91 - 92 95 - 96 181 - 182 192 - 193 196 - 197	Bending Region Analysis