Serine/threonine-Protein Kinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Serine/threonine-Protein Kinase
  Conformer 1
(PDB) 		1zxe (F)
  Conformer 2
(PDB) 		1zy5 (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 158 1.09   651 - 657   792 - 981
2 74 0.57   594 - 650   658 - 791

Sequence


           ________________________________________________________650____657____________________790_______________________________ 
 1zxe(F) : SLRYASDFEEIAVLGQ--fGQVVKARNALDSRYYAIKKIRHTEEKLSTILSEV-lLASLNHQYVVRYYAAWLERRN---kSTLFIQ-eYCENRTLYDLIHSENLNQQRDEYWRLFRQILE 
         :                                                                                                                          
 1zy5(B) : SLRYASDFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRHTEEKLSTILSEVMLLASLNHQYVVRYYAAWLERRNFVkKSTLFIQMEYCENGTLYDLIHSENLNQQRDEYWRLFRQILE 
           ________________________________________________________650____657____________________790_______________________________ 

           ________________________________________________________________________________________________________________________ 
 1zxe(F) : ALSYIHSQGIIHRNLKP-nIFIDESRNVKIGDFGLAKNiGTA-yVATEVLDyNEKID-ySLGIIFFE-iYPFSTG-eRVNILKKLRSVSIEFPPDFDDNK-kVEKKIIRLLIDHDPNKRP 
         :                                                                                                                          
 1zy5(B) : ALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGL----gTAMYVATEVLhYNEKIDMYSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRP 
           ________________________________________________________________________________________________________________________ 

           ______________                                                                                                           
 1zxe(F) : GARTLLNSGWLPVK                                                                                                           
         :                                                                                                                          
 1zy5(B) : GARTLLNSGWLPV*                                                                                                           
           ______________                                                                                                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.0
Translation
(A) 		-0.3
Closure
(%) 		24.0
Bending Residues
( green ) 		  650 - 651
  657 - 658
  790 - 795
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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