Guanine Nucleotide-Binding Protein G(s) Subunit Alpha Isoforms Short

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Guanine Nucleotide-Binding Protein G(s) Subunit Alpha Isoforms Short
  Conformer 1
(PDB) 		3sn6 (A)
  Conformer 2
(PDB) 		1azt (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 191 2.52   37 - 57   209 - 224   229 - 389
2 125 3.54   58 - 208   225 - 228

Sequence


           _______________________________________________57_______________________________________________________________________ 
 3sn6(A) : TEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQ------kATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHA 
         :                                                                                                                          
 1azt(A) : **************************QVYRATHRLLLLGAGESGKSTIVKQMRILHVkATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHA 
           _______________________________________________57_______________________________________________________________________ 

           ________________________________________________201____________________224______________________________________________ 
 3sn6(A) : KALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRV--sGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNM-------tNRLQEAL 
         :                                                                                                                          
 1azt(A) : KALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEAL 
           ________________________________________________201____________________224______________________________________________ 

           ________________________________________________________________________________________________________________________ 
 3sn6(A) : NLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 
         :                                                                                                                          
 1azt(A) : NLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 
           ________________________________________________________________________________________________________________________ 

           ____                                                                                                                     
 3sn6(A) : YELL                                                                                                                     
         :                                                                                                                          
 1azt(A) : Y***                                                                                                                     
           ____                                                                                                                     

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		151.8
Translation
(A) 		-4.8
Closure
(%) 		82.4
Bending Residues
( green ) 		  57 - 89
  201 - 209
  224 - 240
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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