DynDom - Protein Domain Motions

Phosphoenolpyruvate-Protein Kinase (Pts System Ei Component In Bacteria)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphoenolpyruvate-Protein Kinase (Pts System Ei Component In Bacteria)
Conformer 1 (PDB)	2xz7 (A)
Conformer 2 (PDB)	2hwg (A)
Window Length	9
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	270	0.92	253 - 299 310 - 335 337 - 337 349 - 554
2	20	2.12	300 - 309 336 - 336 338 - 348

Sequence

`________________________________________________________________________________________________________________________` `2xz7(A) : **********************************************************************************************************************` `:` `2hwg(A) : ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIlLEDEELEQEIIALIKDKHtADAAAHEVIEGQASALEELDDEYL` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2xz7(A) : ********************************************************************************************************************` `:` `2hwg(A) : KERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTStSIaRSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKrAVQEQV` `________________________________________________________________________________________________________________________` `_______________________________________________296__________309_____________________333____________348__________________` `2xz7(A) : HMEGLKQLKDLPAETPDGKKVMLAANIGTPKDVASALANGAEGVGLFRTEFLYMDRNSLPSEEEQFEAYKEVVEKMGGRPVTIRTLDIGGDKELPYLDMPKEMNPFLGYRAIRLCLDR` `:` `2hwg(A) : ASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLF-dRDALPTEEEQFAAYKAVAEACGSQAVIVRT-dIGGDKELPY-nFPKEENPFLGWRAIRIA-dR` `_______________________________________________296__________309_____________________333____________348__________________` `________________________________________________________________________________________________________________________` `2xz7(A) : PDIFKTQLRAILRASAYGNVQIMYPMISSVEEVRKANSiLEEVKAELDREGVKYDKEIKVGIMVEIPSAAVTADILAKEVDFFSIGTNDLTQYTLAVDRMNEHVKEYYQPFHPAILRLVK` `:` `2hwg(A) : REILRDQLRAILRASAFGKLRI-fPiIS-VEEVRALRKEIEIYKQELRDEGKAFDESIEIGV-vETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGND-iSHLYQP-sPSVLNLIK` `________________________________________________________________________________________________________________________` `______________________________________________________________________________________` `2xz7(A) : MVIDAAHKEGKFAAMCGEMAGDPLAAVILLGLGLDEFSMSATSIPEIKNIIRNVEYEKAKEIAEKALNMSEAREIEKMMKDVIKDI` `:` `2hwg(A) : QVIDASHAEGKWTG-cGELAGDERATLLLLG-gLDEFS-sAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELtLVNKFIEEKT` `______________________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	21.9
Translation (A)	0.2
Closure (%)	95.8
Bending Residues ( green )	296 - 300 309 - 311 333 - 338 348 - 350
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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