DynDom - Protein Domain Motions

Phospholipid-Transporting Atpase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phospholipid-Transporting Atpase
Conformer 1 (PDB)	6k7n (A)
Conformer 2 (PDB)	6k7l (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	751	3.33	37 - 419 483 - 488 646 - 1061
2	208	2.5	420 - 482 489 - 645

Sequence

`________________________________________________________________________________________________________________________` `6k7n(A) : EVRTIFINQPQLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVG` `:` `6k7l(A) : EVRTIFINQP------------aKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVG` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6k7n(A) : DIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRvPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNS` `:` `6k7l(A) : DIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRvPLGADQILLRGAQLRNTQWVHGIVVYTGH--------` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6k7n(A) : TSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEEL` `:` `6k7l(A) : tSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEEL` `________________________________________________________________________________________________________________________` `________________419___________________________________________________482_______________________________________________` `6k7n(A) : GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ---sSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERERDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELL` `:` `6k7l(A) : GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQfSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERERDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELL` `________________419___________________________________________________482_______________________________________________` `_________________________________________________________________________________________________________________645____` `6k7n(A) : NVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQ` `:` `6k7l(A) : NVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQ` `_________________________________________________________________________________________________________________645____` `________________________________________________________________________________________________________________________` `6k7n(A) : DQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVI--fALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQ` `:` `6k7l(A) : DQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINdFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQ` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6k7n(A) : TAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTS` `:` `6k7l(A) : TAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTS` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6k7n(A) : QNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAIPMAPDMSGEAAMLFSSGV` `:` `6k7l(A) : QNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAIPMAPDMSGEAAMLFSSGV` `________________________________________________________________________________________________________________________` `____________________________________________________` `6k7n(A) : FWMGLLFIPVASLLLDVVYKVIKRTAFK************************` `:` `6k7l(A) : FWMGLLFIPVASLLLDVVYKVIKRTAFKlHGYAFSQDENGIVSQSEVIRAYD` `____________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	39.8
Translation (A)	-1.0
Closure (%)	95.7
Bending Residues ( green )	419 - 420 482 - 489 645 - 646
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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