DynDom - Protein Domain Motions

Unconventional Myosin-Ib

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Unconventional Myosin-Ib
Conformer 1 (PDB)	4l79 (A)
Conformer 2 (PDB)	4byf (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	580	3.81	15 - 420 434 - 629
2	107	1.46	421 - 433 630 - 723

Sequence

`________________________________________________________________________________________________________________________` `4l79(A) : EVKSSLLDNMIGVGDTVLLEPL-NEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMS` `:` `4byf(A) : ******DRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `4l79(A) : YVAAVCGKGAEVNQVKEQLLQSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLHKLKLERDFSRYNYL-SLDSAKV` `:` `4byf(A) : FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `4l79(A) : NGVDDAANFRTVRNAMQIVGFSDPEAESVLEVVAAVLKLGNIEFKPESdESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNR` `:` `4byf(A) : SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAA-NEnAQVTTENQLKYLTRLLSVEGSTLREALTHRKIe-----LLSPLNLEQAAYARDALAKAVYSRTFTWLVGK` `________________________________________________________________________________________________________________________` `_______________________________________________________420__________433_________________________________________________` `4l79(A) : INES-----IKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQV` `:` `4byf(A) : INRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDT` `_______________________________________________________419__________432_________________________________________________` `________________________________________________________________________________________________________________________` `4l79(A) : CATHQHFESRMSKCrFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA` `:` `4byf(A) : VKHHPHFLTH----KLADRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSE------kRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQ` `________________________________________________________________________________________________________________________` `_______________________629______________________________________________________________________________________________` `4l79(A) : AHIFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTH` `:` `4byf(A) : PGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQK` `_______________________624______________________________________________________________________________________________` `_____________________` `4l79(A) : FLLMKGLNDIFEAQKIEWHED` `:` `4byf(A) : FL*****************` `_____________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	73.1
Translation (A)	0.5
Closure (%)	37.3
Bending Residues ( green )	420 - 424 433 - 434 629 - 631
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file

Download