Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		6nvl (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 176 1.69   531 - 532   537 - 545   562 - 619   622 - 640   643 - 759
2 78 0.88   468 - 530   533 - 536   546 - 561   620 - 621   641 - 642

Sequence


           ___________________________________________________________________530___536______545_____________561___________________ 
 3gqi(A) : ***ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPG 
         :                                                                                                                          
 6nvl(B) : SEYELPEDPRWELPRDRLVLGKP-------qVVLAEAIGLDK--pNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPG 
           ___________________________________________________________________530___536______545_____________561___________________ 

           ____________________________________619__________________640____________________________________________________________ 
 3gqi(A) : LEFSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 
         :                                                                                                                          
 6nvl(B) : L-----------EqLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGL----------------pVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 
           ____________________________________619__________________640____________________________________________________________ 

           ___________________________________________________________________                                                      
 3gqi(A) : GVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                      
         :                                                                                                                          
 6nvl(B) : GVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT********                                                      
           ___________________________________________________________________                                                      

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		12.9
Translation
(A) 		-0.6
Closure
(%) 		61.2
Bending Residues
( green ) 		  530 - 533
  536 - 537
  545 - 546
  561 - 562
  619 - 622
  640 - 663
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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