Eukaryotic Initiation Factor 4A-I

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Eukaryotic Initiation Factor 4A-I
  Conformer 1
(PDB) 		7ppz (B)
  Conformer 2
(PDB) 		6xki (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 196 1.92   31 - 237
2 162 3.12   238 - 404

Sequence


           ________________________________________________________________________________________________________________________ 
 7ppz(B) : EGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACI---- 
         :                                                                                                                          
 6xki(A) : *********EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTN 
           ________________________________________________________________________________________________________________________ 

           _______________________________________________________________________________________________237______________________ 
 7ppz(B) : ----vQKL---aPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWK 
         :                                                                                                                          
 6xki(A) : VRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWK 
           _______________________________________________________________________________________________237______________________ 

           ________________________________________________________________________________________________________________________ 
 7ppz(B) : LDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD-----iDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE 
         :                                                                                                                          
 6xki(A) : LDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE 
           ________________________________________________________________________________________________________________________ 

           ___________________________                                                                                              
 7ppz(B) : DKRTLRDIETFYNTSIEEMPLNVADLI                                                                                              
         :                                                                                                                          
 6xki(A) : DKRTLRDIETFYNTSIEEMPLNVADLI                                                                                              
           ___________________________                                                                                              

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		85.6
Translation
(A) 		7.5
Closure
(%) 		40.1
Bending Residues
( green ) 		  237 - 238
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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