Mitogen-Activated Protein Kinase 14

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mitogen-Activated Protein Kinase 14
  Conformer 1
(PDB) 		3hl7 (A)
  Conformer 2
(PDB) 		4e5b (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 206 0.83   75 - 85   107 - 321
2 112 0.58   7 - 74   86 - 106   322 - 348

Sequence


           ______________________________________________________________________74_________85__________________106________________ 
 3hl7(A) : **PTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLT 
         :                                                                                                                          
 4e5b(A) : ERPTFYRQEL-kTIWEVPERYQNLSPVGS---gSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNN----qKLT 
           ______________________________________________________________________75_________86__________________107________________ 

           ________________________________________________________________________________________________________________________ 
 3hl7(A) : DDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAaTRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 
         :                                                                                                                          
 4e5b(A) : DDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDF-----rWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________321______________________________                       
 3hl7(A) : ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP                       
         :                                                                                                                          
 4e5b(A) : ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPP*                       
           _________________________________________________________________322______________________________                       

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.4
Translation
(A) 		0.1
Closure
(%) 		93.7
Bending Residues
( green ) 		  74 - 75
  85 - 86
  106 - 107
  321 - 322
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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