N-Lysine Methyltransferase Smyd2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name N-Lysine Methyltransferase Smyd2
  Conformer 1
(PDB) 		5v3h (A)
  Conformer 2
(PDB) 		4ynd (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 210 0.58   8 - 41   56 - 57   109 - 110   113 - 139   175 - 184   197 - 274   278 - 280   364 - 386   390 - 392   397 - 398   403 - 428
2 114 0.56   42 - 55   58 - 108   111 - 112   140 - 174   185 - 196
3 91 0.64   275 - 277   287 - 363   387 - 389   393 - 396   399 - 402

Sequence


           _____________________________________________41____________55__________________________________________________108______ 
 5v3h(A) : KDDDDKMRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILA 
         :                                                                                                                          
 4ynd(A) : ********AEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILA 
           _____________________________________________41____________55__________________________________________________108______ 

           ___________________136___________________________________174_______184_________196______________________________________ 
 5v3h(A) : KQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGE 
         :                                                                                                                          
 4ynd(A) : KQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGE 
           ___________________136___________________________________174_______184_________196______________________________________ 

           _____________________________________274________________________________________________________________________________ 
 5v3h(A) : EVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQ 
         :                                                                                                                          
 4ynd(A) : EVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQ 
           _____________________________________274________________________________________________________________________________ 

           ______363____________________386_______396___402______________________________                                           
 5v3h(A) : DWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIES                                           
         :                                                                                                                          
 4ynd(A) : DWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEI**                                           
           ______363____________________386_______396___402______________________________                                           

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		6.3
Translation
(A) 		0.0
Closure
(%) 		100.0
Bending Residues
( green ) 		  41 - 42
  55 - 58
  108 - 113
  136 - 141
  174 - 175
  184 - 185
  196 - 197
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		8.7
Translation
(A) 		0.1
Closure
(%) 		97.8
Bending Residues
( green ) 		  274 - 275
  277 - 293
  363 - 364
  386 - 387
  389 - 393
  396 - 399
  402 - 403
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Mixed

PyMOL Script

Download and extract PyMOL PML script file Download