Phosphofructokinase (E.C.2.7.1.11)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Phosphofructokinase (E.C.2.7.1.11)
  Conformer 1
(PDB) 		1pfk (A)
  Conformer 2
(PDB) 		1pfk (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 266 0.45   2 - 38   42 - 42   53 - 79   94 - 97   121 - 317
2 50 0.68   39 - 41   43 - 52   80 - 93   98 - 120

Sequence


           _____________________________________38_41_________52______________________76_______________93___________________115____ 
 1pfk(A) : MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPC 
         :                                                                                                                          
 1pfk(B) : MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPC 
           _____________________________________38_41_________52______________________76_______________93___________________115____ 

           ________________________________________________________________________________________________________________________ 
 1pfk(A) : IGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETG 
         :                                                                                                                          
 1pfk(B) : IGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETG 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________                                         
 1pfk(A) : RETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY                                         
         :                                                                                                                          
 1pfk(B) : RETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY                                         
           ________________________________________________________________________________                                         

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		5.3
Translation
(A) 		-0.1
Closure
(%) 		67.0
Bending Residues
( green ) 		  38 - 39
  41 - 43
  52 - 53
  76 - 81
  93 - 98
  115 - 121
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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